Dele Alli broke the deadlock after 55 minutes, before Harry Kane added one from the spot less than three minutes later. The result leaves Spurs just 4 points behind the blues with four matches left.
It is 22 years since Tottenham finished above their neighbours and that they are so far clear this time indicates what is happening at both clubs.
Tottenham are ploughing forwards. Arsenal, meanwhile, struggle in the quicksand. They were competitive at the White Hart Lane for 50 minutes before collapsing to concede two goals in less than two-and-a-half minutes. After that there was no way back and this proved to be another dispiriting day for Wenger’s team.
Both Manchester clubs could only draw earlier in the afternoon but this defeat means Arsenal still managed to lose ground in the contest for top-four places.
Earlier on, Antonio Conte's men beat Everton 3-0 to stay within title reach, courtesy of second half strikes from Pedro, Gary Cahill and Willian.
Meanwhile, Gylfi Sigurdsson's free kick cancelled out Wayne Rooney's opener to earn Swansea a 1-1 draw against Manchester united, and damage United's top four push.
Elsewhere, Manchester City were held to a 2-2 draw with Middlesbrough to delay their top four finish hopes.
-DailyMail